Urinary outcomes of new ultra-minimally invasive treatments for prostate cancers


De Cillis S., Osman N., Guillot-Tantay C., Hervé F., Przydacz M., Tutolo M., ...Daha Fazla

Current Opinion in Urology, cilt.33, sa.6, ss.497-501, 2023 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 33 Sayı: 6
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1097/mou.0000000000001123
  • Dergi Adı: Current Opinion in Urology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.497-501
  • Anahtar Kelimeler: focal therapy, high-intensity focused ultrasound, localized prostate cancer, LUTS, minimally-invasive treatments
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Purpose of reviewThe aim of this narrative review is to evaluate the current available literature on urinary outcomes following cryotherapy and high-intensity focused ultrasound (HIFU) for localized prostate cancer (PCa).Recent findingsThe available literature is heterogeneous in terms of intervention modalities and assessment of urinary outcome measures. Nevertheless, ultra-minimally invasive treatments seem to provide good urinary outcomes. Technological advancement and the adoption of more conservative ablation templates allow for a further reduction of toxicity and better preservation of urinary function. Urinary incontinence occurs in 0-10% of the patients and, is mostly transient. Voiding and storage lower urinary tract symptoms (LUTS) mostly occur in the early postoperative period and rarely require surgical treatment. Focal therapies performed with a salvage intent after external beam radiotherapy have a significantly higher impact on patient's urinary function.SummaryUltra-minimally invasive treatment for PCa show a good safety profile concerning urinary function, but consensus on when and how best to assess this is still lacking. Efforts should be made to standardize the report of preoperative and postoperative urinary function to provide higher level of evidence.