The parametrical investigation of the dilution potentials of some direct compression agents
Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.29, sa.1, ss.21-30, 2000 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 1
- Basım Tarihi: 2000
- Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.21-30
- Anahtar Kelimeler: Dilution potential, Direct compression, Direct compression agents
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The investigation of the excipient properties for Direct Compression (DC) is one of the important steps for the formulation development. The consolidation and the compression properties are compared for Elcema G 250®, Ludipress® and Emcocel® which are used as DC agents. For this purpose, the formulations are diluted by Lactose EP D-30. It was found that, Emcocel has the highest dilution potential, according to the results obtained from In(In Tapp), Heckel and Kawakita equations in all formulations.