Hepatocyte growth factor (HGF) in patients with acute brucellosis
Scandinavian Journal of Infectious Diseases, cilt.36, sa.2, ss.109-113, 2004 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 2
- Basım Tarihi: 2004
- Doi Numarası: 10.1080/00365540410019110
- Dergi Adı: Scandinavian Journal of Infectious Diseases
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.109-113
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
In this prospective study, we investigated the serum levels of hepatocyte growth factor (HGF) and C-reactive protein (CRP) before and after the treatment of patients with acute brucellosis. The study comprised 58 patients with acute brucellosis and 30 healthy volunteers. Pre-treatment serum HGF levels of 58 patients with acute brucellosis (1548.6±220.1) were significantly higher than levels of the control group (401.4±69.7) (p < 0.001). Serum levels of HGF and CRP significantly decreased at the end of the treatment period (p < 0.001). Post treatment, levels did not differ from those of the control group (p > 0.05). Serum HGF levels of patients with acute brucellosis correlated to CRP and ALT levels (r: 0.922, 0.752; p < 0.001, respectively). Our findings suggest that serum HGF levels may be used as a supplementary marker to evaluate the effectiveness of the treatment in patients with acute brucellosis. © 2004 Taylor & Francis.