Coxiella burnetii endocarditis presented with fever of unknown origin in a child with operated congenital heart disease Nedeni bilinmeyen ateşle başvuran opere doǧuştan kalp hastalıǧı olan hastada coxiella burnetii endokarditi


Ceylan Ö., ÖZGÜR S., ÖRÜN U. A., Keskin M., Karademir S., Şenocak F.

Turk Pediatri Arsivi, cilt.48, sa.4, ss.339-341, 2013 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 4
  • Basım Tarihi: 2013
  • Doi Numarası: 10.4274/tpa.942
  • Dergi Adı: Turk Pediatri Arsivi
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.339-341
  • Anahtar Kelimeler: Endocarditis, operated congenital heart disease, Q fever
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Q fever is a zoonotic infection caused by Coxiella Burnetii. Although it is usually asymptomatic, acute form of disease may change from flu-like illness to severe pneumonia. Chronic form may present with vascular disease or endocarditis. A 6-year-old female patient from Sudan followed with the diagnosis of pulmonary atresia and ventricular septal defect was referred to our department because of stenosis in the conduit placed to right ventricular outflow during Rastelli operation performed in Sudan. Six months ago in Jordan, stenting was performed for conduit stenosis, but was unsuccessful. Because of long lasting fever she was treated for culture negative endocarditis in Sudan. In physical examination fever and hepatosplenomegaly were present. Laboratory findings revealed anemia, leukopenia, Coombs' positivity, hypergamaglobulinemia and positive anticardiolipin antibodies but blood cultures were negative. Different antibiotic protocols were administered for culture-negative endocarditis for 2 months, but fever persisted. On 67. day of hospitalization positive antibody titers for Coxiella Burnetii were detected and doxycycline and hydroxychloroquine were started. Here, a case of chronic Q fever due to Coxiella burnetii which is a rare cause of culture-negative endocarditis is presented.