Epidemiological and Prognostic Factors in Pregnancy Diagnosis of SARS-CoV-2 SARS-COV-2 Tanılı Gebelerde Epidemiyolojik ve Prognostik Faktörler
Sakarya Medical Journal, cilt.12, sa.4, ss.703-711, 2022 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 12 Sayı: 4
- Basım Tarihi: 2022
- Doi Numarası: 10.31832/smj.1156358
- Dergi Adı: Sakarya Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.703-711
- Anahtar Kelimeler: Infection, Pneumonia, Pregnancy, Sars-CoV-2
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim Material and Method Results Discussion The aim of this study; is to determine the risk factors, prognostic factors and mortality factors of SARS-CoV-2 virus, which progresses with severe respiratory tract infection, in pregnant women. It is cross-sectional descriptive study that includes pregnant patients over the age of 18 who received inpatient treatment in the Gynecology and Obstetrics Clinic in 2021 and were found to be positive by SARS-CoV-2 PCR test. The clinical features, vital signs, symptoms and laboratory findings of the patients were noted. Statistical analysis of factors affecting mortality was performed. While 74 of the 200 pregnant women included in the study gave birth during the disease, maternal death occurred in 14 of them. The mean saturation value was 88% in those who resulted in maternal death, and it was lower than the other group. In addition, the mean C-Reactive Protein (CRP) of the group with maternal death was significantly higher as 68 mg/L. Comparing maternal death and survivors with univariate tests, it was found that fever of 37.8 and above increased mortality, those with cough and shortness of breath had a significantly higher mortality rate, those with high liver function tests (LFT) had a significantly higher mortality rate, and India (Delta) variant mortality rate was also found to be significantly higher. It was observed that the mortality rate increased 4.9 times in pregnant women who presented with fever of 37.8°C and above, and 3.5 times increased in those infected with Delta variant. It was concluded that the mortality decreased 1.33 times for each 1 unit height of saturation. The clinical follow-up parameters and the deepening of laboratory findings in SARS-CoV-2 infected pregnant women are directly related to the prognosis of the disease and the possibility of maternal mortality. In terms of the usability of these results, there is a need for compilation and meta-analysis of many literature studies.