Comparison of the 2022 ACR/EULAR classification criteria with the 1990 ACR classification criteria for Takayasu arteritis
Sarcoidosis Vasculitis and Diffuse Lung Diseases, cilt.42, sa.3, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 42 Sayı: 3
- Basım Tarihi: 2025
- Doi Numarası: 10.36141/svdld.v42i3.17094
- Dergi Adı: Sarcoidosis Vasculitis and Diffuse Lung Diseases
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Anahtar Kelimeler: Takayasu arteritis, classification, sensitivity, specificity
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background and aim: Takayasu arteritis (TAK) mostly affects the aorta and its major branches and has an unclear origin. This study aimed to compare the 1990 American College of Rheumatology (ACR) classification criteria with the 2022 ACR/European League Against Rheumatism (EULAR) classification criteria for TAK on the basis of clinical data analysis of patients with TAK and other major vascular diseases. Methods: This retrospective study was conducted in a single-center. The results included 34 TAK patients routinely followed at a tertiary rheumatology center from October 2017 to February 2024. The accuracy, sensitivity, specificity, positive predictive values (PPV), negative predictive values (NPV), and area under the receiver operating characteristic (ROC) curve (AUC) of the classification criteria were compared. Results: The sensitivity (91.2%), specificity (90.9%), PPV (93.9%), NPV (86.9%), accuracy (94.4%) and AUC (0.983 (0.957-0.998)) of the 2022 ACR/EULAR classification criteria for TAK were higher than those of the 1990 ACR classification criteria for TAK (76.4%, 86.3%, 88.9%, 64.2% and 0.75, respectively), and the difference in AUC was statistically significant (0.860 (0.757-0.963), p < 0.001). Conclusions: The study concluded that the 2022 ACR/EULAR classification criteria were more appropriate for the patient population under investigation and exhibited superior classification performance in comparison to those in 1990. These findings are supported by clinical experience. It is evident that the findings of this study require further validation through the implementation of prospective multicentre studies with increased patient numbers.