Nanomaterials for drug delivery systems
New Developments in Nanosensors for Pharmaceutical Analysis, Elsevier, ss.273-301, 2019
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2019
- Doi Numarası: 10.1016/b978-0-12-816144-9.00009-2
- Yayınevi: Elsevier
- Sayfa Sayıları: ss.273-301
- Anahtar Kelimeler: Dendrimers, Liposomes, Micelles, Nanocarriers, Nanomaterials, Nanoparticles
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Nanotechnology is an expanding field, especially in engineering, physics, chemistry, biology, and medicine. Nanotechnology is unique in that it signifies not a single specific area, but a vast variety of disciplines ranging from basic material science to personal care applications. The application of nanotechnology to drug delivery is commonly expected to change the landscape of the drug and biotechnology industries for the foreseeable future. Moreover, nano-sized drug delivery systems have already had a great impact on pharmaceutical technology by improving the effect of drugs and enabling new therapies. Nanoparticles used in drug delivery are nano-sized in at least one dimension and consist of different materials. Based on the application of the preparations, there are varied forms of nanoparticles that have been synthesized and evaluated to improve drug bioavailability, overcome drug resistance, and reduce drug toxicity. To achieve effective drug delivery, it is essential to understand the biological environment-nanoparticle interaction, drug release from nanoparticles, multiple drug administration, and the stability of therapeutic agents and molecular mechanisms of cell behavior in the disease under consideration. Due to their tremendous properties, nanoparticles have been utilized to treat a variety of diseases and disorders by their attachment to biologically active molecules, targeting sequences, fluorescent or other imaging devices, biocompatible coatings, and others.