CT-based radiomics for predicting stone-free rate after ESWL: a systematic review and meta-analysis


Talyshinskii A., Ali S., Gauhar V., Güven S., Somani B. K., SARICA K., ...Daha Fazla

World Journal of Urology, cilt.43, sa.1, 2025 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 43 Sayı: 1
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1007/s00345-025-05933-6
  • Dergi Adı: World Journal of Urology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Gender Studies Database, MEDLINE
  • Anahtar Kelimeler: Urolithiasis, ESWL, CT, Radiomics, SFR
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Purpose: To evaluate the prognostic significance of computed tomography (CT)-based radiomic features of urinary stones in predicting stone-free rate (SFR) after extracorporeal shockwave lithotripsy (ESWL) and laser lithotripsy. Methods: A systematic literature search of several databases using Boolean operators was performed according to PRISMA guideline and registered in PROSPERO (CRD420250650566). Studies using CT-based radiomics to predict SFR after ESWL or laser lithotripsy and reporting area under the receiver operating characteristic curve (AUC) with 95% confidence intervals (CI) were included. CLAIM and PROBAST checklists were used to assess transparency and and and risk of bias, respectively. A random-effects meta-analysis was performed to pool AUC estimates and assess heterogeneity. Results: Seven studies were selected and analyzed, of which five described radiomic prediction for ESWL and were analyzed in the meta-analysis. The pooled AUC for radiomics-based models predicting SFR after ESWL was 0.883 (95% CI: 0.840–0.927), with low heterogeneity (I2 = 24.3%) and a prediction interval of 0.77–0.96. All studies were rated at high risk of bias with moderate compliance. Conclusion: Adding CT-based radiomic features of stones to other clinical and radiologic parameters can predict SFR after ESWL with an AUC of > 0.85. However, the results are based on a small number of studies mostly with a high risk of bias, so follow-up studies performed according to the tenets of using radiomic analysis are needed.