Evaluation of the Long-Term Clinical Results of 3 Patients Implanted with the Argus II Retinal Prosthesis


Güven D., Düzgün E., Kutucu O. K., Gül C.

Turkish Journal of Ophthalmology, cilt.53, sa.1, ss.58-66, 2023 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.4274/tjo.galenos.2022.53598
  • Dergi Adı: Turkish Journal of Ophthalmology
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.58-66
  • Anahtar Kelimeler: Retinitis pigmentosa, retinal prosthesis, Argus II implant, optical coherence tomography
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

This study presents the long-term clinical results of Argus II retinal prosthesis implantation in eyes with light perception and projection in 3 patients with end-stage retinitis pigmentosa. No conjunctival erosion, hypotony, or implant displacement was observed during postoperative follow-up. The electrical threshold values were lower in the macular region and higher close to the tack fixation region and peripherally. Optical coherence tomography scans showed fibrosis and retinoschisis formation at the retina-implant interface in two cases. This was attributed to mechanical and electrical effects on the tissue due to the active daily use of the system and the electrodes’ proximity to the retina. The patients were able to integrate the system into their daily lives and perform activities that they could not do before. Studies on retinal prostheses for the rehabilitation of hereditary retinal diseases are ongoing, so both social and clinical observations and experiences related to the implant are valuable.