Oral sucrose and non-nutritive sucking goes some way to reducing pain during retinopathy of prematurity eye examinations


DİLLİ D., Ilarslan N. E. Ç., KABATAŞ E. U., ZENCİROĞLU A., Şimşek Y., OKUMUŞ N.

Acta Paediatrica, International Journal of Paediatrics, cilt.103, sa.2, 2014 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 103 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1111/apa.12454
  • Dergi Adı: Acta Paediatrica, International Journal of Paediatrics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Eye examination, Non-nutritive sucking, Pain, Retinopathy of prematurity, Sucrose
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Aim To evaluate the efficacy of oral sucrose combined with non-nutritive sucking for reducing pain associated with retinopathy of prematurity screening. Methods This was a randomised controlled study of 64 infants undergoing eye examination for retinopathy of prematurity screening. Topical anaesthetic (Proparacaine; Alcaine® drop 0.5%: ALCON CANADA Inc., Mississauga, Canada) was applied 30 sec before the eye examination in all infants. The infants in intervention group (Group 1, n = 32) received 0.5 mL/kg of 24% sucrose with a pacifier. The control group (Group 2, n = 32) received 0.5 mL/kg of sterile water with a pacifier. Results The groups had similar gestational ages (28.5 ± 2.8 weeks), mean birthweight (1304 ± 466 g) or corrected gestational age (35.4 ± 3.7 weeks) at examination. The intervention group had a significantly lower mean Premature Infant Pain Profile score during examination of the first eye, following insertion of the speculum (Group 1:13.7 ± 2.1 vs. Group 2:16.4 ± 1.8, p = 0.001). Conclusion Although sucrose combined with non-nutritive sucking modestly reduces pain scores during eye examinations, there is need to further studies to explore significant pain relief for infants undergoing retinopathy of prematurity screening. © 2013 Foundation Acta Pædiatrica. Published by John Wiley & Sons Ltd.