Etiological and Clinical Characteristics of Cases with Pancreatitis Pankreatit Tanılı Olguların Etiyolojik ve Klinik Özellikleri


Bilen P., URGANCI N., Usta M., Güller D.

Medical Journal of Bakirkoy, cilt.21, sa.1, ss.97-103, 2025 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 1
  • Basım Tarihi: 2025
  • Doi Numarası: 10.4274/bmj.galenos.2024.2023.10-7
  • Dergi Adı: Medical Journal of Bakirkoy
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.97-103
  • Anahtar Kelimeler: Acute pancreatitis, etiology, treatment, children
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: This study aimed to evaluate the clinical, laboratory, and etiological features of children with pancreatitis. Methods: Sixty-three patients who were followed up between 2005 and 2019 and diagnosed with pancreatitis were enrolled in the study. The patients were classified into groups 1 and 2, with acute and chronic pancreatitis, respectively. The demographic, etiological, clinical features, and laboratory parameters were evaluated retrospectively. Results: The mean age was 11.1±2.3 (range 3.9-16.7 years) and M/F was 1.6. The most common causes were biliary sludge, gallstones (14.2%), and familial Mediterranean fever (FMF) (11%). Group 1 included 46 patients (73.1%) and group 2 included 17 patients with acute recurrent pancreatitis and 7 patients with chronic pancreatitis. The most common causes were idiopathic (50%), biliary sludge and stones (15.3%), and infections (13%) in group 1 and idiopathic (17.7%), FMF (17.7%), cystic fibrosis (17.7%), and genetics (17.7%) in group 2. There were no statistically significant differences in laboratory parameters between the groups (p>0.05). Conclusion: In developing countries where consanguineous marriage is common, genetic diseases, especially FMF, should be considered in patients presenting with abdominal pain, amylase, and lipase elevation and diagnosed with pancreatitis.