The Efficacy of Posterior Subtenon Triamcinolone Acetonide Injection in Treatment of Irvine-Gass Syndrome


Erden B., ÇAKIR A., Aslan A. C., Bölükbaşı S., ELÇİOĞLU M. N.

Ocular Immunology and Inflammation, cilt.27, sa.8, ss.1235-1241, 2019 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 8
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1080/09273948.2019.1620786
  • Dergi Adı: Ocular Immunology and Inflammation
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1235-1241
  • Anahtar Kelimeler: corticosteroids, irvine-gass syndrome, posterior subtenon, pseudophakic macular edema, triamcinolone
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Purpose: To evaluate the efficacy and safety of posterior 40 mg subtenon triamcinolone acetonide (PST) injection in treating Irvine-Gass syndrome. Methods: The retrospective study included 21 patients (mean age: 76 ± 8.2) with a treatment-naïve eye subjected to topical anesthesia and injection of 40 mg/ml triamcinolone via a blunt tip SubTenon cannula through a single inferonasal peritomy. Best corrected visual acuity (BCVA; logMAR), intraocular pressure (IOP), biomicroscopic and funduscopic findings, and optical coherence tomography (OCT) measurements were recorded. Results: Baseline central macular thickness decreased from 431 ± 136 µm to 300 ± 67 µm (1st month; p =.002), to 292 ± 56 µm (3rd month; p =.002), and to 299 ± 66 µm (6th month; p =.005). Mean BCVA increased from 0.71 ± 0.23 to 0.27 ± 0.11, 0.19 ± 0.06, and 0.24 ± 0.17, respectively (all visits; p < 0.001). Mean IOP values did not change significantly (p =.12). Conclusion: PST injection is an effective and safe treatment for Irvine-Gass syndrome.