ABO blood group mismatched hematopoietic stem cell transplantation


Tekgündüz S. A., ÖZBEK N. Y.

Transfusion and Apheresis Science, cilt.54, sa.1, ss.24-29, 2016 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 54 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.transci.2016.01.008
  • Dergi Adı: Transfusion and Apheresis Science
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.24-29
  • Anahtar Kelimeler: Allogeneic hematopoietic stem cell transplantation, Engrafment, Transplantation complications, ABO mismatch, Transfusion
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Apart from solid organ transplantations, use of ABO-blood group mismatched (ABO-mismatched) donors is acceptable in hematopoietic stem cell transplantation (HSCT) patients. About 20-40% of allogeneic HSCT recipients will receive grafts from ABO-mismatched donors. ABO incompatible HSCT procedures are associated with immediate and late consequences, including but not restricted to acute or delayed hemolytic reactions, delayed red blood cell recovery, pure red cell aplasia and graft-versus-host disease. This review summarizes the current knowledge about consequences of ABO-mismatched HSCT in terms of associated complications and will evaluate its impact on important outcome parameters of HSCT.