Evaluation of cytotoxic effect of garlic on human gingival fibroblasts: A preliminary study
Gulhane Medical Journal, cilt.55, sa.4, ss.276-280, 2013 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 55 Sayı: 4
- Basım Tarihi: 2013
- Doi Numarası: 10.5455/gulhane.28177
- Dergi Adı: Gulhane Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.276-280
- Anahtar Kelimeler: Chlorhexidin gluconat, Cytotoxicity, Garlic, Human gingival fibroblast
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
In this study we aimed to evaluate the cytotoxic effect of garlic extract on human gingival fibroblasts. Garlic extracts were prepared at 5 different concentrations as 12.5%, 6.25%, 3.12%, 1.5%, and 0.6%. Cytotoxic effects of garlic and clorhexidine gluconat (CH) on human gingival fibroblasts were evaluated by agar diffusion method at 24 h. Garlic extracts concentrations at 6.25, 3.12, and 1.5% were not found cytotoxic on human gingival fibroblasts, whereas concentration at 12.5% was found cytotoxic, this effect was found less cytotoxic than CH. According to results of this study we could suggest that Garlic would have a promising role in the future for oral health, if appropriate solutions can be prepared. © Gülhane Askeri Ti{dotless}p Akademisi 2013.