Evaluation of the prognostic effectiveness of liver metastasis volume by volumetric measurement in colorectal cancer
Future Oncology, cilt.20, sa.38, ss.3133-3140, 2024 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 38
- Basım Tarihi: 2024
- Doi Numarası: 10.1080/14796694.2024.2406221
- Dergi Adı: Future Oncology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.3133-3140
- Anahtar Kelimeler: colorectal cancer tumor volume, liver metastasis volume, volumetric tumor measurement method
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: To evaluate the relationship between liver metastasis volume and survival in colorectal cancer patients using the volumetric measurement method. Methods: 114 colorectal cancer patients with isolated liver metastases were included in the study. Liver tumor volume, total liver volume were calculated from the patients images at the time of diagnosis. Vitrea 7.14 imaging software was used for liver volume analysis and volume analysis of each metastasis. Results: Median overall survival(OS) in the group with tumor volume <42 ml3 was 30.98 months In the group with tumor volume ≥42 ml3, median OS was 16.36 months (p: 0.001). In patients who underwent metastasectomy, the median OS in the group with a tumor volume <42 ml3 was 52.3 months, the median OS in the group with a tumor volume ≥42 ml3 was 22.2 months. In patients who did not undergo metastasectomy, the median OS in the <42 ml3 group was 20.23 months, the median OS in the ≥42 ml3 group was 15.63 months. Conclusion: In our study, we found that liver metastasis volume was prognostic for OS. It is argued that tumor volume measurement by volumetric measurement is a widely used method in the decision for metastasectomy in liver metastatic colorectal cancer patients.