Intermittent - low dose G - CSF treatment in a patient with chronic neutropenia


Yetgin S., ÖZBEK N. Y.

Turkish Journal of Pediatrics, cilt.40, sa.3, ss.421-424, 1998 (SCI-Expanded, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 3
  • Basım Tarihi: 1998
  • Dergi Adı: Turkish Journal of Pediatrics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.421-424
  • Anahtar Kelimeler: chronic neutropenia, intermittent-low dose G-CSF
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Chronic neutropenia in childhood has many definable causes and thus a clear cause cannot be identified in a large group of patients. Since the committed stem cell is involved in this disorder, growth factors such as granulocyte colony-stimulating factor (G-CSF) may play an important role in the treatment of severely affected children. Because of the side effects and cost, the use of G-CSF should be restricted to a minimum dose. Here we report a child with chronic neutropenia in whom intermittent-low doses of G-CSF were successfully used over a long period.