Metabolic Syndrome and Menopause: The Impact of Menopause Duration on Risk Factors and Components
International Journal of Women's Health, cilt.16, ss.1249-1256, 2024 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16
- Basım Tarihi: 2024
- Doi Numarası: 10.2147/ijwh.s460645
- Dergi Adı: International Journal of Women's Health
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1249-1256
- Anahtar Kelimeler: metabolic syndrome, menopause, anthropometric measurements
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: This study was undertaken to investigate the impact of menopause duration on the risk factors and components of metabolic syndrome (MetS). Patients and Methods: Women aged between 45 and 60 years participated in the study. Participants were split into two groups based on the duration of menopause. Women who had been menopausal for 1 to ≤5 years constituted Group 1, while women with 6–10 years of menopause duration formed Group 2. Results: Significant differences were observed between the two groups for various factors associated with MetS, including anthro-pometric measurements, biochemical markers, and blood pressure. The conicity index, weight-to-hip ratio, waist-to-height ratio, visceral adiposity index (VAI), and menopause duration were associated with increased risk of MetS. Our multivariate logistic regression model showed that women with elevated VAI had a 2.073-fold (95% CI: 1.73–2.48, p<0.001) increased risk of MetS, while women with menopause duration more than 5 years had a 6.44-fold (95% CI: 3.336–12.45, p<0.001) increased risk of MetS. Conclusion: The duration of menopause was found to be linked to a higher risk of MetS. Our results emphasize the importance of monitoring and managing metabolic health in women during the menopausal period, particularly those with extended menopause duration.