Biocompatible Nanopolymers in Drug Delivery Systems and Their Recent Electrochemical Applications in Drug Assays
Handbook of Polymer and eramic Nanotechnology: Volume 1,2, Springer International Publishing Ag, ss.875-894, 2021
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2021
- Doi Numarası: 10.1007/978-3-030-40513-7_24
- Yayınevi: Springer International Publishing Ag
- Sayfa Sayıları: ss.875-894
- Anahtar Kelimeler: Drug delivery, Nanotechnology, Polymer
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Nanopolymers are one of the most important nanomaterials for the future. Nanopolymers are declared as particle dispersions or solid particles with size at the nanoscale. Nanopolymers have come into prominence due to the fact that they give some opportunities such as building nanoscale parts, self-assembly structures at controllable and variable scales, the downscaling of size, and new phase transitions. Nanopolymers can enhance high efficiency and selectivity to active compounds. Nanopolymers are constructed from biocompatible and biodegradable polymers which are one of the new trends of biomaterial where the drug is dissolved, entrapped, encapsulated, or attached to a nanoparticle matrix. They can be used as green chemistry in different applications for medicine, engineering, and pharmacy. Electrochemical methods have many advantages such as less time-consuming analysis, the usage of mini-portable and of affordable analyzer, and determination of sample without interferences. These methods give much information about the electrochemical behavior of a drug. Therefore, it can be sorted out to understand its in vivo redox reaction and pharmacological activity. The interest in developing electrochemical sensor systems is sharply increasing at clinical assays and in environmental monitoring. Biodegradable nanopolymers are promising carriers for many active compounds and are gaining importance over application of traditional oral and intravenous methods in regard to efficiency and selectivity. When biocompatible materials are applied to the body, it is expected to perform a desired response without any side effects. In this chapter, commonly used biocompatible polymers in drug delivery as nanoparticles were described. Also, we described the recent electrochemical applications of biocompatible and biodegradable nanopolymeric materials for pharmaceutical assays.