Procalcitonin Prokalsitonin
SENDROM, cilt.14, sa.12, ss.81-90, 2002 (Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 14 Sayı: 12
- Basım Tarihi: 2002
- Dergi Adı: SENDROM
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.81-90
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Recently a new marker called procalcitonin has added to the list of infectious disease markers. As a calcitonin propeptide procalcitonin is produced by C cells in tiroid gland. PCT can be used as a marker of systemic enflematory states triggered by bacterial infections (sepsis, septic shock). Infections that is not systemic or localized to an organ give rise to mild elevations in PCT level. Bacterial toxins play the major role in PCT production. Disease states that has bacterial toxins inits etiology (sepsis, septic schock, multiple organ disfunction) is characterized by such an high PCT levels like 10 to 100 ng/ml. Increase in PCT levels during disease states otoimmun neoplastic and viral infections ones are mild. Chronic non bacterial inflamations and allergic reactions have uncharged PCT level. These important properties of PCT is not possessed by many other infection markers.