Usefulness of CHA2DS2-VASc Score to predict clinical outcomes of patients undergoing carotid artery stenting
International Journal of Cardiovascular Imaging, cilt.37, sa.3, ss.783-789, 2021 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 3
- Basım Tarihi: 2021
- Doi Numarası: 10.1007/s10554-020-02078-y
- Dergi Adı: International Journal of Cardiovascular Imaging
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.783-789
- Anahtar Kelimeler: CHA(2)DS(2)-VASc , score, Carotid stenting, Mortality, Stroke
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The CHA2DS2-VASc score predicts stroke and mortality risk in several cardiovascular diseases regardless of atrial fibrillation. In this study, we aimed to investigate the ability of CHA2DS2-VASc score to predict in-hospital and long-term outcomes in patients undergoing carotid artery stenting (CAS). The study population included 558 patients undergoing CAS. The patients were stratified into three groups based on their CHA2DS2-VASc scores [low (≤ 2, n = 123), moderate (3–5, n = 355) and high (6–8, n = 80)]. In-hospital and 3-year outcomes were compared between the groups. In-hospital rates of ipsilateral and major strokes and death were significantly different between the groups (1.6% vs. 3.9% vs. 16.2%; 1.6% vs. 4.5% vs. 16.2%; 0.8% vs. 3.1% vs. 13.8%, p < 0.001 for all, respectively). At 3 years of follow-up, rates of ipsilateral and major strokes and death were significantly increased in patients with highscore compared to those with moderate and low scores (1.6% vs. 5.8% vs. 13%, p = 0.005; 0.8% vs. 5.2% vs. 13%, p = 0.001; 1.6% vs. 8.4% vs. 15.9%; p = 0.002, respectively). After adjusting for multi-model Cox regression analysis, CHA2DS2-VASc score persisted as an independent prognostic factor for mortality and major stroke in patients undergoing CAS. Higher CHA2DS2-VASc score predicted increased risk of in-hospital and 3- year stroke and mortality in patients undergoing CAS.