Assessment of D-dimer levels in pregnant women diagnosed with COVID-19: A case-control study
Journal of Maternal-Fetal and Neonatal Medicine, cilt.36, sa.2, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 2
- Basım Tarihi: 2023
- Doi Numarası: 10.1080/14767058.2023.2231123
- Dergi Adı: Journal of Maternal-Fetal and Neonatal Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, MEDLINE
- Anahtar Kelimeler: COVID-19, D-dimer, Pregnancy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: We aimed to evaluate D-dimer levels in pregnant women diagnosed with COVID-19. Methods: This single-center study was carried out in a tertiary center hospital serving as a pandemic hospital. 151 pregnant women with COVID-19 diagnosis were included as the study group, and 70 healthy pregnant women as the control group. The data were analyzed separately in 3 different trimesters of pregnancy. Results: Of the 221 pregnant women included in the study, 151 had a diagnosis of COVID-19. 70 healthy pregnant women were taken as the control group. It was observed that D-dimer values in pregnancy increased as the trimesters progressed. No significant difference was observed when this was compared with pregnant women with COVID-19 (p =.428,.75,.927 according to the 1st, 2nd and 3rd trimesters, respectively). Conclusion: The diagnosis of pulmonary embolism is difficult due to the lack of reliable alternative D-dimer thresholds for pregnant patients. On the other hand, D-dimer elevation continues to be a sign of poor prognosis in patients with COVID-19. The situation remains uncertain in patients who are pregnant and have COVID-19. Maybe D-dimer value should be removed from being a poor prognosis criterion in pregnant women.