Oral and intradialytic parenteral essenial amino acid therapy in hemodialysis patients with malnutrition Malnutrisyonlu kronik hemodiyaliz hastalarinda oral ve parenteral esansiyel amino asit tedavisi
Ondokuz Mayis Universitesi Tip Dergisi, cilt.15, sa.4, ss.306-311, 1998 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 4
- Basım Tarihi: 1998
- Dergi Adı: Ondokuz Mayis Universitesi Tip Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.306-311
- Anahtar Kelimeler: Essential amino acid, Hemodialysis, Malnutrition
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
After malnutrition has been seen to be an important factor of morbidity and mortality on hemodialysis patients, various oral and parenteral nutritional therapies have been developed to administrate to these patients. In this study, in order to investigate the effects of the oral and parenteral essential amino acid (EAA) therapy on the treatment of malnutrition in hemodialysis patients the half of 20 hemodialysis patients with malnutrition were treated with 0.9 gr/kg/week oral EAA (oral group) and the other half were treated with same dose parenteral EAA (parenteral group). Pretreatment and posttreatment values were compared by Wilcoxon T test in oral and parenteral groups. After these therapies, in both of the groups, there were no significant statistical increases in anthropometric parameters. While there were statistically significant increases in only serum calcium (p = 0.028) and lymphocyte counts (p = 0.028) in oral group, there were statistical significant increases in more parameters in parenteral group such as in serum albumin (p = 0.048), creatinine (p = 0.006), cholesterol (p = 0.006) levels and lymphocyte count (p = 0.006). These results suggest that parenteral EAA therapy is more comfortable and effective than oral EAA therapy in the treatment of hemodialysis patients with malnutrition.