Coenzyme Q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury

Erol, Bulent; Bozlu, Murat; HANCI, VOLKAN; Tokgoz, Husnu; BEKTAŞ, Sibel; Mungan, Gorkem

doi:10.1016/j.fertnstert.2009.07.981

Coenzyme Q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia/reperfusion injury

Erol B., Bozlu M., HANCI V., Tokgoz H., BEKTAŞ S., Mungan G.

Fertility and Sterility, cilt.93, sa.1, ss.280-282, 2010 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 93 Sayı: 1
Basım Tarihi: 2010
Doi Numarası: 10.1016/j.fertnstert.2009.07.981
Dergi Adı: Fertility and Sterility
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.280-282
Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

In this experimental study, we assessed the preventive effects of coenzyme Q10 (CoQ10) in a rat model of ischemia/reperfusion injury. The results of this study show that CoQ10 administration before the reperfusion period of testicular torsion provides a significant decrease in testicular lipid peroxidation products and expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and germ cell-specific apoptosis. © 2010 American Society for Reproductive Medicine.