An uncommon cause of multiple pulmonary nodules: Pulmonary hyalinizing granuloma


Taci H. N., Söyler Y., Uğurman F., AĞAÇKIRAN Y., AYDOĞDU K.

Hippokratia, cilt.23, sa.1, ss.33-36, 2020 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 1
  • Basım Tarihi: 2020
  • Dergi Adı: Hippokratia
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, EMBASE
  • Sayfa Sayıları: ss.33-36
  • Anahtar Kelimeler: Multiple pulmonary nodules, Pulmonary hyalinizing granuloma
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Background: Pulmonary hyalinizing granuloma (PHG) is a rare, benign disease of unknown etiology, characterized by single or multiple randomly distributed pulmonary nodules. Mediastinal or hilar lymphadenopathy is not a feature in the absence of concomitant infection. Case report: We describe an interesting case of PHG in a 66-year-old woman who had multiple bilateral pulmonary nodules and hilar lymph nodes, which demonstrated mild to moderate fluorodeoxyglucose (FDG) uptake on the positron emission tomography (PET) scan. The hilar lymph node enlargement shown was due to anthracosis. The patient underwent wedge resection, and histopathological examination confirmed the lesion to be PHG. Conclusion: PHG is a benign fibro-sclerosing disease that should be in the differential diagnosis of multiple pulmonary nodules, which may exhibit FDG uptake. Histological examination of appropriate specimens is required to establish an accurate diagnosis of PHG.