Invasive esophageal Aspergillosis associated with acute myelogenous leukemia: Successful therapy with combination caspofungin and liposomal amphotericin B
Pediatric Hematology and Oncology, cilt.24, sa.1, ss.63-68, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 24 Sayı: 1
- Basım Tarihi: 2007
- Doi Numarası: 10.1080/08880010601001412
- Dergi Adı: Pediatric Hematology and Oncology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.63-68
- Anahtar Kelimeler: acute myclogenous leukemia, Aspergillus, caspofungin, liposomal amphotericin B
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aspergillosis is one of the most common invasive fungal infections in patients with leukemia. In this patient group, this form of Aspergillus infection is a life-threatening condition with a mortality of 50-100%. The lungs are most often affected, but the esophagus can also be involved.The authors report the case of a child with leukemia who developed invasive esophageal aspergillosis. The condition was diagnosed by microscopic examination of endoscopic biopsy specimens. The patient was already receiving empirical liposomal amphotericin B when the diagnosis was made, so a second antifungal (caspofungin) was added to the regimen. This combination was successful. This case to demonstrates a case of successful treatment of invasive esophageal aspergillosis using combination therapy of liposomal amphotericin B and caspofungin. Copyright © Informa Healthcare.