Neurobrucellosis in an endemic area of brucellosis
Scandinavian Journal of Infectious Diseases, cilt.35, sa.2, ss.94-97, 2003 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 2
- Basım Tarihi: 2003
- Doi Numarası: 10.1080/0036554021000027000
- Dergi Adı: Scandinavian Journal of Infectious Diseases
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.94-97
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Central nervous system involvement occurs less than 5% of patients with brucellosis. A prospective analysis of 73 patients with brucellosis identified 13 (17.8%) neurobrucellosis cases from February 2001 to May 2002. 10 patients had chronic meningitis and 3 acute meningitis. Two patients had only psychiatric disorders. Cranial nerve involvement was observed in 3 patients (6th, 7th and 8th nerves). Three patients had positive blood cultures and 3 others had positive cerebrospinal fluid (CSF) cultures. 12 patients had positive agglutination titres in CSF. All patients received antibiotic therapy with ceftriaxone, rifampicin and doxycycline initially, and after 1 month they were continued with rifampicin and doxycycline up to 4 months. All patients were completely cured. Hearing loss developed in 1 patient as a sequela.