The correlation between depression and anxiety levels and quality of life in essential thrombocytosis and polycythemia vera patients Esansiyel trombositoz ve polisitemi vera hastalarında depresyon ve anksiyete düzeyleri ile yaşam kalitesi arasındaki ilişki
Pamukkale Medical Journal, cilt.13, sa.3, ss.785-793, 2020 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13 Sayı: 3
- Basım Tarihi: 2020
- Doi Numarası: 10.31362/patd.677864
- Dergi Adı: Pamukkale Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.785-793
- Anahtar Kelimeler: Anxiety, depression, polycythemia, quality of life, thrombocytosis
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: This study was conducted to assess the correlation between depression and anxiety and quality of life (OQL) in essential thrombocytosis (ET) and polycythemia vera (PV) patients. Material and methods: The study was conducted in the Hematology Clinic of a training and research hospital in the Aegean region of Turkey between July 2016 and May 2017. A total of 60 patients (30 ET and 30 PV) were included in the study. Eastern Cooperative Oncology Group (ECOG), Karnofsky scale, EORTC QLQ-C30, and Hospital Anxiety and Depression Scale (HADS) were used to collect the data. The data was analyzed using SPSS 20.0 packaged software. The results were assessed at the confidence interval of 95% and significance level of p<0.05. Results: The average age of ET and PV patients were 60.3±11.2/years and 58.7±11.7/years, respectively. ECOG and Karnofsky performance scores were similiar in two groups. There was no significant difference between the groups in terms of EORTC QLQ-C30 overall QOL and HADS-D scores. HADS-A score mean rank was higher in PV patients (p=0.000) (ET:22.1 in, PV:38.9). Score mean rank of EORTC QLQ-C30 fatigue, dyspnea and financial difficulty subscales (41.5, 38.2, 38.1) in ET patients and score mean rank of EORTC QLQ-C30 cognitive functioning, pain and diarrhea subscales (43.8, 38.9, 41.1) in PV patients were higher (p=0.000). There was a significant correlation between HADS-A and HADS-D scores and EORTC QLQ-C30 overall QOL score (p<0.01) in ET patients. Conclusion: Cognitive function, pain and diarrhea subscale scores of anxiety level and quality of life were higher in PV patients. Fatigue, dyspnea and financial difficulties subscale scores of the quality of life were higher in ET patients. As the depression and anxiety levels of both ET and PV patients increase, quality of life decreases.