Using Positron Emission Tomography/Computed Tomography to Diagnose Atypically Located Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type, Mimicking Necrotising Soft Tissue Infection Pozitron Emisyon Tomografi/Bilgisayarlı Tomografi Kullanılarak Tanı Konulan, Nekrotizan Yumuşak Doku Enfeksiyonunu Taklid Eden Atipik Yerleşimli Nazal Tip, Ekstranodal NK/T Hücreli Lenfoma
Gazi Medical Journal, cilt.36, sa.4, ss.463-466, 2025 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 4
- Basım Tarihi: 2025
- Doi Numarası: 10.12996/gmj.2024.4207
- Dergi Adı: Gazi Medical Journal
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.463-466
- Anahtar Kelimeler: Extranodal NK/T-cell lymphoma, positron emission tomography/computed tomography, skin
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Extranodal natural killer/T-cell lymphoma (ENKTL) is an Epstein-Barr virus-associated, rapidly spreading lymphoproliferative disorder with a poor prognosis. Although it usually manifests with nasal involvement, different clinical and histopathological features can be detected. In nasal form, it may be confused with mucormycosis. Identifying the appropriate biopsy site is crucial for an accurate ENKTL-nasal type diagnosis, and positron emission tomography/computed tomography (PET/CT) can facilitate this. In this paper, we share the case of a 73-year-old male who presented with nasal and skin involvement, and was diagnosed with an unfavourable prognosis using PET/CT-guided biopsy. Unfortunately, the initial biopsies were inconclusive and led to an unnecessary antimicrobial treatment. Combining fluorodeoxyglucose PET/CT images allowed us to pinpoint the biopsy location and assess the depth of tissue infiltration, resulting in a successful biopsy even in this rare case.