Prognostic value of inflammatory and radiologic markers in pediatric bell’s palsy: a retrospective study
European Archives of Oto-Rhino-Laryngology, cilt.283, sa.1, ss.157-166, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 283 Sayı: 1
- Basım Tarihi: 2026
- Doi Numarası: 10.1007/s00405-025-09653-w
- Dergi Adı: European Archives of Oto-Rhino-Laryngology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
- Sayfa Sayıları: ss.157-166
- Anahtar Kelimeler: Pediatric bell's palsy, Facial paralysis, Computed tomography, Inflammation, Facial nerve
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose: To evaluate the prognostic significance of inflammatory markers, computed tomography (CT)-based facial nerve measurements, and clinical parameters in pediatric patients with Bell’s palsy. Methods: In this retrospective study, 136 patients aged 4–18 years diagnosed with Bell’s palsy were evaluated. Clinical data included age, sex, affected side, initial House-Brackmann (HB) grade, recovery grades at one month and final follow-up, presence of pain, and treatment timing. Inflammatory markers—mean platelet volume (MPV), neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein-to-albumin ratio (CAR)— were calculated from laboratory data obtained at admission. Facial nerve-to-facial canal (FN/FC) ratios were measured via CT in five regions. The control group included 70 age-matched children with normal CT scans obtained for non-specific complaints such as headache. Recovery was categorized as full (HB 1), partial (improved but not grade 1), or poor. Results: Initial HB grade was significantly correlated with both one-month (r = 0.67, p < 0.001) and final recovery (r = 0.33, p < 0.001). CAR was weakly correlated with one-month recovery (r = 0.224, p = 0.0089) but not long-term outcome. MPV, NLR, and PLR showed no significant prognostic value. FN/FC ratios were significantly higher in the labyrinthine, geniculate, and tympanic regions on the paralyzed side compared to both the control group and non-paralyzed side. However, no correlations were found between FN/FC ratios and recovery. A moderate correlation was observed between initial HB grade and tympanic FN/FC ratio (r = 0.321, p = 0.001). Conclusion: Initial clinical severity best predicts recovery in pediatric Bell’s palsy. Inflammatory and radiologic parameters offer limited prognostic value and warrant cautious interpretation.