Predictors and prognostic significance of troponin-I release following elective coronary angioplasty


Izgi A., Tanalp A., KIRMA C., Dundar C., Oduncu V., Ackakoyun M., ...Daha Fazla

Journal of International Medical Research, cilt.34, sa.6, ss.612-623, 2006 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 6
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1177/147323000603400606
  • Dergi Adı: Journal of International Medical Research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.612-623
  • Anahtar Kelimeler: cardiac tropinin-I, coronary angioplasty, percutaneous coronary intervention, ischaemic heart disease, long-term outcome
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

The objective of this study was to investigate the predictors and prognostic significance of post-procedural cardiac troponin (cTn)-I elevations in a consecutive series of patients who underwent elective percutaneous coronary intervention (PCI). cTn-I was measured in 100 patients immediately before and within 24 h after the elective PCI. Post-procedural cTn-I elevation was observed in 27 of the 100 patients. In multivariate analysis, basal haemoglobin values and the number of repeated balloon dilatations were found to be independent predictors of cTn-I elevation. During the follow-up period of 12 ± 1.2 months, the cTn-I-positive group bad more major adverse cardiovascular events than the cTn-I-negative group (33.3% versus 16.4%, respectively), but the difference was not significant. An increase in cTn-I levels following elective PCI procedures was frequent but dip not predict a poor long-term outcome. Copyright © 2006 Cambridge Medical Publications.