Verapamil and nimodipine do not improve renal function during cardiopulmonary bypass
Acta Anaesthesiologica Italica / Anaesthesia and Intensive Care in Italy, cilt.49, sa.2, ss.173-177, 1998 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 49 Sayı: 2
- Basım Tarihi: 1998
- Dergi Adı: Acta Anaesthesiologica Italica / Anaesthesia and Intensive Care in Italy
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.173-177
- Anahtar Kelimeler: Calcium antagonists, Cardiopulmonary bypass, Kidney function, Nimodipine, Verapamil
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
The effects of verapamil and nimodipine in addition to low-dose dopamine treatment on renal function were investigated. Seventy-five patients undergoing cardiopulmonary bypass (CPB) were randomly allocated into 3 groups to receive verapamil, nimodipine, or saline during CPB. Creatinine clearance (Clcr), fractional excretion of sodium (FENa), and urine output were studied preoperatively, intraoperatively (preCPB, duringCPB, postCPB) and postoperatively. There were no significant differences between the groups with regard to Clcr, FENa and urine output. We conclude that neither verapamil nor nimodipine administration improve Clcr, FENa, or urine output in patients undergoing CPB.