Diffuse Myocardial Uptake of 99mTc-HDP in Multiple Myeloma


Demirel K., Sadic M., Korkmaz M., Comak A., Atilgan H. I., KOCA G.

Nuclear Medicine and Molecular Imaging, cilt.47, sa.3, ss.208-211, 2013 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s13139-013-0209-5
  • Dergi Adı: Nuclear Medicine and Molecular Imaging
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.208-211
  • Anahtar Kelimeler: Technetium-99m hydroxymethylene diphosphonate (Tc-99m-HDP), Technetium-99m bone agents, Myocardial uptake, Multiple myeloma
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Soft tissue uptake is a rare finding in bone scintigraphy, with an incidence of 2%. Although the mechanism has not yet been fully clarified, several causes have been reported for this unusual uptake pattern. This paper presents a case of diffuse myocardial accumulation of technetium-99m hydroxymethylene diphosphonate (99mTc-HDP) without either solid/visceral organ or soft tissue with multiple myeloma (MM) in skeletal scintigraphy. A 93-year-old man with hypertension and chronic heart failure for 14 years underwent bone scanning due to a 2-month history of back pain within a 1-year period of MM. Three hours later, 99mTc-HDP late static images showed diffuse myocardial radiotracer accumulation and there were no other sites of abnormal soft tissue or visceral uptake. Myocardial accumulation had disappeared on 24-h delayed static images. This accumulation was thought to be related with AL-type amyloidosis associated with MM. © 2013 Korean Society of Nuclear Medicine.