Nonfunctioning adrenocortical carcinoma in a child
Pediatric Pathology and Molecular Medicine, cilt.22, sa.5, ss.405-410, 2003 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 5
- Basım Tarihi: 2003
- Doi Numarası: 10.1080/15227950307702
- Dergi Adı: Pediatric Pathology and Molecular Medicine
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.405-410
- Anahtar Kelimeler: adrenocortical carcinoma, p53 mutation
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Pediatric nonfunctioning adrenocortical carcinoma is a very rare tumor. A 4-year-old girl was admitted complaining of abdominal pain. Physical examination revealed an abdominal mass. There were no clinical or laboratory signs of hormonal abnormality. Abdominal ultrasonography revealed a polylobular mass. Intravenous pyelography showed marked compression of the kidney by a tumor. The tumor was excised together with the right kidney. The histopathological diagnosis was adrenocortical carcinoma. Although there is a greater incidence of germ line p53 mutations with adrenocortical carcinoma, the tumor suppressor gene p53 was not mutated in our case. The girl died 2 months after surgery from complications of chemotherapy.