Idiopathic granulomatous mastitis: A rare benign inflammatory disease masquerading as breast carcinoma
Acta Medica Mediterranea, cilt.31, sa.1, ss.189-193, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 1
- Basım Tarihi: 2015
- Dergi Adı: Acta Medica Mediterranea
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.189-193
- Anahtar Kelimeler: Idiopathic, granulomatous, mastitis, breast, cancer
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aims: Idiopathic granulomatous mastitis is an uncommon, benign, chronic inflammatory breast disease. In this study, we report our experience with idiopathic granulomatous mastitis of the breast and include a summary of the current literature to provide a reference for the management of this rare clinical entity Materials and methods: A retrospective study included 24 women who met the required histological criteria of idiopathic granulomatous mastitis and who were treated at Izmir Bozyaka Education and Research Hospital, Department of Surgery between January 2000 - 2014. Clinical data of the presentation, results of the diagnostic workup, histopathology, treatment and outcome were analyzed by review of medical records. Results: The mean age at diagnosis was 36 years (range 21-51 years). The most common presenting symptoms were a palpable mass in the breast (18/24, 75%) and pain, erythema, and fistula formation (6/24, 25%). An ultrasonography was performed in all 24 cases and mammographic examination of the breast was performed in 10 (41%) patients. The major radiographic finding is an ill-defined mass, occurring in eight patients In 10 cases the preoperative diagnosis was suspicion of breast malignancy. All patients underwent a wide local excision, and were diagnosed with idiopathic granulomatous mastitis by pathologists. Conclusions: Idiopathic granulomatous mastitis is a rare and challenging condition. Therefore, a proper treatment method should be chosen on a case-by-case basis. Idiopathic granulomatous mastitis is a diagnosis of exclusion with histology of breast cancer. Surgical intervention in the form of wide local excision is necessary and there is a place for adjuvant treatment as steroid treatment in selected and recurrent cases.