The role of concentrated growth factor (CGF) in type 1 tympanoplasty
European Archives of Oto-Rhino-Laryngology, cilt.283, sa.8, ss.4947-4954, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 283 Sayı: 8
- Basım Tarihi: 2026
- Doi Numarası: 10.1007/s00405-026-10224-w
- Dergi Adı: European Archives of Oto-Rhino-Laryngology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
- Sayfa Sayıları: ss.4947-4954
- Anahtar Kelimeler: CGF, Tympanoplasty, Underlay, Graft
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: The aim of this study was to investigate the efficacy of concentrated growth factor (CGF) in type 1 tympanoplasty. Methods: This study represents a retrospective analysis of a non-randomized interventional cohort study, included 60 patients who underwent primary type 1 tympanoplasty between November 2024 and July 2025. The patients were divided into those who received only a cartilage graft (n = 30) and those who received a cartilage graft and CGF (n = 30). The incidence rates of residual tympanic membrane perforation, audiological outcomes, and postoperative infection rates were compared. Results: The incidence rate of residual perforation was significantly lower in the CGF group than in the cartilage-only group. The audiological outcomes showed no significant differences between the groups. Postoperative infection was observed less frequently in the CGF group. Conclusion: CGF may represent a promising adjunct in type 1 tympanoplasty by potentially supporting graft integration and reducing residual perforation rates.