Platelet-to-Haemoglobin Ratio Predicts the Development of Left Ventricular Apical Thrombus
Cardiovascular Journal of Africa, cilt.36, sa.2, ss.192-196, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 36 Sayı: 2
- Basım Tarihi: 2025
- Doi Numarası: 10.5830/cvja-2025-021
- Dergi Adı: Cardiovascular Journal of Africa
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
- Sayfa Sayıları: ss.192-196
- Anahtar Kelimeler: apical thrombus, myocardial infarction, platelet-to-haemoglobin ratio
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Apical thrombus (AT) is a severe complication in myocardial infarction (MI), increasing the risk of thromboembolic events. Platelet-to-haemoglobin ratio (PHR) is a novel, inexpensive predictor of cardiovascular outcomes. This study explores the association between PHR and AT in MI patients. Materials & methods: This retrospective study included 690 anterior MI patients (314 patients with AT and 376 patients without AT as a control group). Blood samples were analysed to calculate PHR, and echocardiographic evaluations identified AT. Logistic regression and ROC analysis determined independent predictors and the optimal PHR cut-off value for AT. Results: PHR was significantly higher in the AT group (2.03 ± 0.64 vs. 1.85 ± 0.50; p < 0.001). Multivariate analysis identified PHR, proximal LAD lesions, and lower LVEF as independent predictors. The PHR cut-off of 1.88 showed 69.3% sensitivity and 68.4% specificity. Conclusion: PHR is a simple, accessible marker for predicting AT in MI patients. Its use may improve early risk stratification and clinical outcomes.