α-Interferon and isoprinosine in adult-onset sub acute sclerosing panencephalitis
Journal of the Neurological Sciences, cilt.162, sa.1, ss.62-64, 1999 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 162 Sayı: 1
- Basım Tarihi: 1999
- Doi Numarası: 10.1016/s0022-510x(98)00302-5
- Dergi Adı: Journal of the Neurological Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.62-64
- Anahtar Kelimeler: subacute sclerosing panencephalitis (SSPE), adult-onset, alpha-interferon, isoprinosine
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
We report eight patients with adult-onset subacute sclerosing panencephalitis (SSPE), of which, four were treated with oral isoprinosine and four with intraventricular α-interferon plus oral isoprinosine. One of the four patients treated with oral isoprinosine died within two months, and the disease progressed in three patients. Of the four patients treated with oral isoprinosine plus intraventricular α-interferon, one showed mild progression, one remission, and the remaining two showed stabilization. The group of patients is relatively small, but our results suggest that treatment with oral isoprinosine plus α-interferon is effective for SSPE.