Relationship between blood viscosity and no-reflow phenomenon in ST-segment elevation myocardial infarction performed in primary percutaneous coronary interventions


YILDIRIM A., KÜÇÜKOSMANOĞLU M., Koyunsever N. Y., ÇEKİCİ Y., Belibagli M. C., Kilic S.

Biomarkers in Medicine, cilt.15, sa.9, ss.659-667, 2021 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 9
  • Basım Tarihi: 2021
  • Doi Numarası: 10.2217/bmm-2020-0772
  • Dergi Adı: Biomarkers in Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.659-667
  • Anahtar Kelimeler: no-reflow phenomenon, primary percutaneous coronary intervention, ST-elevated myocardial infarction, whole-blood viscosity
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Background: This study aimed to analyze the associations between no-reflow (NR) phenomenon development and whole-blood viscosity in patients with ST-elevated myocardial infarction. Methods: A total of 217 patients with ST-elevated myocardial infarction were included. whole-blood viscosity values were assessed using hematocrit and total protein values, and low shear rate (LSR) and high shear rate (HSR) were calculated. Results: The average LSR and HSR values of the study group were significantly higher than the control group (p < 0.001). Multivariate logistic regression analysis showed that both HSR (odds ratio: 4.957; p < 0.001) and LSR (odds ratio: 1.114; p < 0.001) were independent predictors for NR development. Conclusion: This study found that increased blood viscosity was an independent predictor for NR development.