Transfusion transmitted virus and its clinical implications Transfusion transmitted virus (TTV) ve klinik önemi
SENDROM, cilt.16, sa.5, ss.79-84, 2004 (Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 16 Sayı: 5
- Basım Tarihi: 2004
- Dergi Adı: SENDROM
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.79-84
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Transfusion Transmitted Virus (TTV) is a hepatotropic virus and its transmission is by fecal-oral, intravenous and transplacental route. It is firstly isolated from 5 patients that were diagnosed as a post-transfusional non-A, non-G hepatitis in Japan. TTV is a single-strained, linear DNA virus which is similar to Circoviridae family. After replication in hematopoietic cells, the virus attacks liver. Although the risk of hepatocytic injury is lesser, the TTV is mostly seen in patients that have been exposed transfusions, transplantations and hemodialysis. Many cases of TTV infection are asymptomatic and the serum level of liver enzymes are normal. The recognization of TTV is good for explaining the cause of post-transfusional hepatitis, however there are still much more to be known about viruses that might cause hepatitis.