Cytotoxic Lesions of the Corpus Callosum: Two Case Reports
Journal of the College of Physicians and Surgeons Pakistan, cilt.33, sa.1, ss.135-137, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 1
- Basım Tarihi: 2023
- Doi Numarası: 10.29271/jcpspcr.2023.135
- Dergi Adı: Journal of the College of Physicians and Surgeons Pakistan
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, MEDLINE, Veterinary Science Database
- Sayfa Sayıları: ss.135-137
- Anahtar Kelimeler: Corpus callosum, Cytotoxiu lesions, Hyponatraemia, Magnetic resonance imaging
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
The corpus callosum (CC), conventionally divided into four parts (rostrum, genu, body, and splenium), connects the corresponding centres in the right and left cerebral hemispheres. Cytotoxic lesions of the corpus callosum (CLOCC) are unusual clinical conditions and manifest with diverse presentations. We, herein, present two cases of CLOCC. In the first case, a 61-year female patient presented to the Emergency Department (ED) with nausea, dizziness, and syncope. The second case involved a 35-year male patient admitted to the ED with diarrhoea and urinary incontinence. The definitive aetiology of CLOCC could not be determined. The possible causes included systemic, metabolic, toxic, infectious, and seizure-related conditions. Both of the cases exhibited hyponatraemia. Diagnosis involves identifying acute diffusion restriction in the splenium of the CC (SCC) using diffusion magnetic resonance imaging (MRI). CLOCC should be considered in patients with undiagnosed neurological signs and symptoms.