The Efficacy of the Naples Prognostic Score in Patients with Carotid Stenosis
Arquivos de Neuro-Psiquiatria, cilt.84, sa.3, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 84 Sayı: 3
- Basım Tarihi: 2026
- Doi Numarası: 10.1055/s-0046-1817033
- Dergi Adı: Arquivos de Neuro-Psiquiatria
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Psycinfo, Directory of Open Access Journals
- Anahtar Kelimeler: Carotid Stenosis, Ischemic Stroke, Inflammation, Nutritional Status
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background The Naples Prognostic Score (NPS) is widely used, especially in cancer patients. Although it has been emphasized that this scoring system has a strong prognostic power for cardiovascular diseases, studies on cerebrovascular patients are quite limited. Objective To investigate whether there is a relationship between the level of carotid artery stenosis and the NPS. Methods Measurements were taken and recorded using venous blood samples taken from the patients at the time of their first hospital admission. Patients with NPS of 0, 1, and 2 were classified as the low Naples group. Patients with NPS of 3 and 4 were classified as the high Naples group. When analyzing the patients, comparisons were made according to these two separate groups. Results According to the cut-off values of the neutrophil-to-lymphocyte ratio (NLR; > 2.96), the lymphocyte-to-monocyte ratio (LMR; < 4.44), total cholesterol (TC; < 180), and albumin (< 4), the NLR was high in 261 (40%) patients, the LMR was low in 113 (17.3%) subjects, the TG level was low in 215 (32.9%) participants, and the albumin level was low in 247 (48.4%) individuals. The NPS was calculated according to the sum of the NLR (> 2.96), LMR (< 4.44), TG (< 180) and albumin (< 4) cut-off values, and it was 0 in 17 (2.6%) patients, 1 in 87 (13.3%), 2 in 212 (32.5%), 3 in 214 (32.8%), and 4 in 123 (18.8%) subjects. Conclusion The current study revealed a significant correlation between the degree of carotid stenosis and the NPS, which can be used as a tool to predict the severity of carotid stenosis.