Follow-up of patients with surgical colorectal cancer resection
Colon Polyps and Colorectal Cancer: Second Edition, Springer International Publishing Ag, ss.419-433, 2020
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2020
- Doi Numarası: 10.1007/978-3-030-57273-0_21
- Yayınevi: Springer International Publishing Ag
- Sayfa Sayıları: ss.419-433
- Anahtar Kelimeler: Cancer survivors, Carcinoembryonic antigen, Colorectal cancer, Computed tomography, Endoscopy, FDG-PET/CT, Follow-up, Recurrence, Surveillance
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Colorectal cancer (CRC), which is one of the most frequently seen cancers worldwide, is also one of the major causes of cancer-related deaths. With the advancement of diagnostic technology and effective implementation of screening programs, the detection and surgical treatment of CRCs at a resectable stage conveys a greater possibility. With the increase in resection rates over time in CRCs, the question of what should be the most appropriate follow-up has emerged. The survival and recurrence rates of CRCs after resection are directly related to the stage of the disease. The 5-year survival rate is 75% in stage 1, and approximately 5% in stage 4 CRC. Recurrence rates also increase in proportion to the stage of the disease. More than 90% of these recurrences, which develop intraluminally and extraluminally, develop in the first 5 years, most frequently within the first 3 years. In the light of these data, the aim of the follow-up after resection is to detect recurrences in the period when recurrences are asymptomatic and suitable for resection. Many important institutions from Europe, the USA, and Japan have published follow-up guidelines, whose main purpose is to improve survival, the majority of which contain recommendations concerning stage 2 and stage 3 CRCs. Although postresection follow-up guidelines somewhat differ from each other, they are concerned with some parameters as patient's history, physical examination, carcinoembryonic antigen (CEA) level, thoracic and abdominal computed tomography, colonoscopy, and rectosigmoidoscopy. In addition, in the follow-up guidelines of CRC, though not taken its place in routine follow-up procedures yet, the use of FDG-PET/CT in the follow-up of these patients will apparently increase over time.