Mantle cell lymphoma presenting with acute bilateral ophthalmoplegia
Turk Oftalmoloiji Dergisi, cilt.47, sa.4, ss.235-237, 2017 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 47 Sayı: 4
- Basım Tarihi: 2017
- Doi Numarası: 10.4274/tjo.80557
- Dergi Adı: Turk Oftalmoloiji Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.235-237
- Anahtar Kelimeler: Mantle cell lymphoma, ophthalmoplegia, blepharoptosis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
A 72-year-old woman presented with acute onset of double vision, bilateral complete blepharoptosis, and nearly complete ophthalmoplegia. Orbital and brain magnetic resonance imaging were normal. Further investigation revealed bicytopenia with hepatosplenomegaly. Liver biopsy revealed mantle cell lymphoma. Cytology later showed the presence of mantle cells in cerebrospinal fluid analysis. Her ophthalmoplegia improved from her first cycle of systemic and intrathecal chemotherapy. To the best of our knowledge, this is the second case in the literature of mantle cell lymphoma with central nervous system involvement presenting with ophthalmoplegia. This symptom should be considered one of the initial signs of mantle cell lymphoma.