Effects of whole-body vibration on plasma sclerostin level in healthy women
Turkish Journal of Medical Sciences, cilt.44, sa.3, ss.404-410, 2014 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 44 Sayı: 3
- Basım Tarihi: 2014
- Doi Numarası: 10.3906/sag-1302-88
- Dergi Adı: Turkish Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.404-410
- Anahtar Kelimeler: Sclerostin, cyclic mechanical loading, vibration, osteocyte, bone
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background/aim: To determine whether plasma sclerostin levels are affected by applying whole-body vibration treatments. Materials and methods: Following a pilot study, the present prospective, randomized, controlled single-blind study was performed on 16 healthy volunteer women (ages 20 to 40 years). Subjects were randomly divided into 2 groups, and whole-body vibration was applied to the treatment group but not to the controls. The plasma sclerostin levels were measured before the treatment and at the 10th minute after whole-body vibration on the 1st, 2nd, and 5th days of application. Results: The plasma sclerostin level measured at 10 min after the whole-body vibration treatment increased 91% (P = 0.024) on the 1st day and decreased 31.5% (P = 0.03) on the 5th day in the whole-body vibration group. In the control group, there was no change in the plasma sclerostin level at any time. A progressive increase in baseline plasma sclerostin levels during the 5 days of vibration sessions was also found. Conclusion: Our study demonstrated that whole-body vibration can change plasma sclerostin levels, and that this change is detectable 10 min after whole-body vibration treatments. © TÜBİTAK.