Broadband targeted UVB phototherapy for localized vitiligo: A retrospective study


Akar A., TUNCA M., Koc E., Kurumlu Z.

Photodermatology Photoimmunology and Photomedicine, cilt.25, sa.3, ss.161-163, 2009 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1111/j.1600-0781.2009.00426.x
  • Dergi Adı: Photodermatology Photoimmunology and Photomedicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.161-163
  • Anahtar Kelimeler: vitiligo, treatment, UVB, targeted phototherapy
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Phototherapy with ultraviolet B (UVB) or PUVA has been used in the treatment of vitiligo for many years. The aim of this study was to analyze retrospectively the efficacy and safety of targeted broadband UVB phototherapy in patients with localized vitiligo. Thirty-two patients (14 male, 18 female), aged 18-65 years, were treated with Daavlin T500x High Dose Targeted Phototherapy System. Patients were treated twice or thrice weekly, totaling 20 to 60 sessions. Out of 32 total patients, only four patients (12.5%) showed visible repigmentation. In two patients, repigmentation was more than 75%. Other two patients showed mild repigmentation (less than 25%). All the lesions responsive to treatment were facial lesions. Mild adverse events recorded in 3 of 32 patients. Although safety of targeted broadband UVB phototherapy in the treatment of localized vitiligo is good, its therapeutic effectiveness is limited and depends on the locations of vitiligo lesions. © 2009 John Wiley & Sons A/S.