Adipose derived stromal vascular fraction cells therapy in hemophilic arthropathy: A case report
Agri, cilt.37, sa.1, ss.62-65, 2025 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 37 Sayı: 1
- Basım Tarihi: 2025
- Doi Numarası: 10.14744/agri.2022.37043
- Dergi Adı: Agri
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, MEDLINE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.62-65
- Anahtar Kelimeler: Hemophilic arthrosis, intraarticular injection, mesenchymal stem cells, stromal vascular fraction
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Stromal vascular fraction (SVF) is a heterogeneous collection of cells obtained from adipose tissue through lipoaspiration and is an alternative intraarticular treatment option, especially in osteoarthritis (OA). The anti-inflammatory and extracellular tissue repair-stimulating properties of SVF increase its effectiveness in regeneration and repair mechanisms. One of the most common symptoms of hemophilia A and B is hemophilic arthropathy (HA). If HA is not adequately managed initially, patients may require major surgery, including total joint arthroplasty. In a 34-year-old male patient who was treated with intraarticular adipose-derived SVF with the diagnosis of hemophilia B and right grade 4 hemophilic knee arthrosis, clinical and radiological scores showed significant improvement in the 3rd month, 6th month, and 1st year controls after the procedure. Intraarticular adipose-derived SVF treatment should be kept in mind as an effective treatment option with minimal invasiveness and few side effects in HA that does not respond to conservative treatments.