A Rare Presentation of Alveolar Soft Part Sarcoma in the Bladder
International Journal of Surgical Pathology, cilt.34, sa.1, ss.158-161, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 34 Sayı: 1
- Basım Tarihi: 2026
- Doi Numarası: 10.1177/10668969251348240
- Dergi Adı: International Journal of Surgical Pathology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Academic Search Ultimate (EBSCO), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
- Sayfa Sayıları: ss.158-161
- Anahtar Kelimeler: alveolar soft part sarcoma (ASPS), bladder cancer, partial cystectomy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Alveolar soft part sarcoma (ASPS) is a rare and distinctive subtype of soft tissue sarcoma accounting for <1% of all sarcomas. Characterized by the t(X;17)(p11;q25) translocation, it typically affects the extremities in younger individuals. This case report presents a bladder ASPS in a 45-year-old woman, a rare occurrence, developing as a second primary malignancy following breast cancer treatment. Histopathological analysis, immunohistochemistry and molecular diagnostics confirmed the diagnosis. The patient underwent partial cystectomy with clear surgical margins and remained recurrence-free 38 months post-resection. This report highlights the diagnostic challenges, therapeutic strategies, and the importance of long-term surveillance for bladder ASPS.