The relationship between QT prolongation and short term prognosis in patients with subarachnoid hemorrhage due to aneursym rupture
Turkiye Klinikleri Journal of Medical Sciences, cilt.29, sa.1, ss.123-127, 2009 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 1
- Basım Tarihi: 2009
- Dergi Adı: Turkiye Klinikleri Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.123-127
- Anahtar Kelimeler: Subarachnoid hemorrhage, mortality, electrocardiography
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Electrocardiographic (ECG) abnormalities and rhythm disorders are frequently observed in the acute phase of spontaneous subarachnoid hemorrhage (SAH). The pathophysiology of these abnormalities is considered to be related with the imbalance in autonomic cardiovascular control. There is no study yet showing the prognostic relevance of corrected QT interval (QTc) prolongation following subarachnoid hemorrhage in the Turkish population. Material and Methods: This retrospective study consisted of 33 SAH patients (7 male and 26 female) who were operated for aneurysm rupture in the Department of Neurosurgery between 2003 and 2005. Early ECG alterations of patients were evaluated by a cardiologist who was blinded for the prognosis of patients. We examined the relationship between prognosis and ECG findings. Results: Of the 33 SAH patients, those who died during hospitalization constituted the mortal group (n= 9), and the remaining patients the as survived group (n= 24). Baseline characteristics of the 2 groups were similar, however mean QTc values of mortal patients were significantly higher than in patients that survived (p= 0.034). In correlation analysis, we found that QTc interval was significantly correlated with Glasgow outcome scale (r= -0.39, p= 0.024). Conclusion: ECG should be evaluated in terms of QTc prolongation in SAH patients as a clinical prognostic finding. Copyright © 2009 by Türkiye Klinikleri.