Bilberry inhibits angiogenesis in chick chorioallontoic membrane
BioFactors, cilt.33, sa.3, ss.161-164, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 3
- Basım Tarihi: 2008
- Doi Numarası: 10.1002/biof.5520330301
- Dergi Adı: BioFactors
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.161-164
- Anahtar Kelimeler: Angiogenesis, bilberry, anti-angiogenesis
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Angiogenesis is the process of generating new blood vessels from preexisting vessels and is considered essential in many pathological conditions. Bilberry has been traditionally used as a folk medicine for some countries. The purpose of the present study was to evaluate the effect of bilberry in chick chorioallantoic membrane angiogenesis model in vivo. In this well characterized model, bilberry inhibited angiogenesis in a concentration-dependent manner. Compared with the normal group, bilberry group has significant decreased vessels proliferation. These results provide evidence that bilberry inhibits angiogenesis and may be useful for treating angiogenesis-dependent human diseases. © 2008 - IUBMB/IOS Press and the authors. All rights reserved.