Predicting Contrast-Induced Acute Kidney Injury in ST-Segment Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention: A Novel Approach
Heart Lung and Circulation, cilt.34, sa.8, ss.821-829, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 34 Sayı: 8
- Basım Tarihi: 2025
- Doi Numarası: 10.1016/j.hlc.2025.01.005
- Dergi Adı: Heart Lung and Circulation
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE
- Sayfa Sayıları: ss.821-829
- Anahtar Kelimeler: Contrast-induced acute kidney injury, Percutaneous coronary intervention, ST segment elevation myocardial infarction, Albumin, Bilirubin, ALBI score
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: Contrast-induced acute kidney injury (CI-AKI) is a significant clinical challenge, particularly in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). This study aimed to evaluate the predictive value of the albumin-bilirubin (ALBI) score for CI-AKI in this high-risk population. Method: We retrospectively analysed 2,011 patients with STEMI who underwent primary PCI, excluding those with severe renal or liver conditions. CI-AKI occurred in 9.1% of patients. Higher ALBI scores were significantly associated with the development of CI-AKI. Results: Receiver-operating characteristic analysis revealed that an ALBI score > −2.54 predicted CI-AKI with 70% sensitivity and 61.5% specificity. Logistic regression identified the ALBI score as an independent predictor of CI-AKI (odds ratio 9.731; 95% confidence interval 5.873−16.123; p<0.001). Conclusions: These findings suggest that the ALBI score, a simple and cost-effective tool, could be integrated into clinical practice to better predict and manage CI-AKI in patients with STEMI undergoing PCI. Further research is warranted to confirm these results and explore the underlying mechanisms.